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LONDON (AP) — Three scientists who discovered powerful techniques to decode and even design novel proteins — the building blocks of life — were awarded the Nobel Prize in chemistry Wednesday.

WINNIPEG — The Manitoba government is looking to tighten the rules around the sale of machetes, swords and other long-bladed weapons.

NEW YORK (AP) — U.S. stocks set records Wednesday after the latest wild swerves for Chinese stocks left few ripples in markets worldwide. The S&P 500 rose 0.7% to top the all-time high it had set last week.

North American stock markets gained ground on Wednesday thanks to continued optimism about the strength of the U.S. economy. The S&P/TSX composite index was up 152.39 points at 24,224.90. In New York, the Dow Jones industrial average was up 431.

RIO DE JANEIRO (AP) — The social media platform X began returning to Brazil on Wednesday, after remaining inaccessible for more than a month due to a clash between its owner, Elon Musk, and a justice on the country’s highest court.

Global hitmaker Bryan Adams is adding his voice to opposition over new federal regulations on streaming.

TORONTO — Siskinds LLP says a $70.25 million class-action settlement has been reached with TD Asset Management over commissions paid to discount brokers.

NEW DELHI (AP) — Ratan Tata, a former chairman of India’s oldest conglomerate Tata Sons, died at a Mumbai hospital on Wednesday night. He was 86.

TORONTO — Ontario launched a review of the province's 37 non-Indigenous children's aid societies Wednesday after Premier Doug Ford suggested they are being financially mismanaged, but the unions representing CAS workers say it is a mere "smokescreen.

TORONTO — The research that won Geoffrey Hinton a Nobel Prize for physics was the product of plenty of work carried out before artificial intelligence was the buzzword it is today.